Thomas Ramey Watson

Lymphoma Drug Shrinks Dog Tumors, Could Lead to Human Treatment

There are many kinds of cancers of the immune system, but one, Activated B-Cell Diffuse Large

B-Cell Lymphoma, or ABC-DLBCL, is particularly common and pernicious.

Researchers at the University of Pennsylvania’s School of Veterinary Medicine have shown for the first time that dogs that develop this disease spontaneously share the same aberrant activation of a critical intracellular pathway with humans.

They also found that a drug designed to disrupt this pathway helps to kill tumor cells in the dogs’ cancerous lymph nodes.

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