Thomas Ramey Watson

Mystery Ingredient in Coffee Boosts Protection Against Alzheimer’s Disease

The new study does not diminish the importance of caffeine to protect against Alzheimer’s. Rather it shows that caffeinated coffee induces an increase in blood levels of a growth factor called GCSF (granulocyte colony stimulating factor). GCSF is a substance greatly decreased in patients with Alzheimer’s disease and demonstrated to improve memory in Alzheimer’s mice. A just-completed clinical trial at the USF Health Byrd Alzheimer’s Institute is investigating GCSF treatment to prevent full-blown Alzheimer’ s in patient

s with mild cognitive impairment, a condition preceding the disease.

The results of that trial are currently being evaluated and should be known soon.

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