From the crises in the Middle East to mass shootings in U.S. schools to the reckless striving for wealth and world domination, there is one overarching theme that almost never gets media coverage—the sense of insignificance that drives destructive acts. As a depth psychologist with many years of experience, I can say emphatically that the sense of being crushed, humiliated and existentially unimportant are the main factors behind so much that we call psychopathology.